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Difference between Gastric and Duodenal Ulcers

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  • Clinical Skills
  • 2023-03-05 16:10:43

Gastric and duodenal ulcers are both types of peptic ulcers, which are open sores that develop in the lining of the stomach or small intestine. However, there are some key differences between the two types of ulcers:


Gastric ulcers occur in the stomach, while duodenal ulcers occur in the first part of the small intestine called the duodenum.


The symptoms of gastric and duodenal ulcers can be similar, including abdominal pain, bloating, nausea, and loss of appetite. However, the pain caused by a gastric ulcer tends to be felt in the upper middle part of the abdomen, while the pain caused by a duodenal ulcer is usually felt in the upper right part of the abdomen.


The most common cause of gastric and duodenal ulcers is an infection with the bacterium Helicobacter pylori (H. pylori). Other factors that may contribute to the development of ulcers include long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs), excessive alcohol consumption, smoking, and stress.


The treatment of gastric and duodenal ulcers is similar and may include antibiotics to treat H. pylori infection, proton pump inhibitors (PPIs) to reduce acid production in the stomach, and lifestyle changes such as avoiding NSAIDs and reducing stress.

In summary, while gastric and duodenal ulcers share many similarities, they differ in their location, symptoms, and causes

    Textbook of pathophysiology, Harrison's textbook of internal medicine, Medscape

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