- Antihistamines
- Pharmacology
Antihistamines Pharmacology PPT
- Topic: Pharmacology
- Subtopic: Antihistamines
- Posted 2024-10-26 22:50:43
Presentation Overview
The slide covers comprehensive content on <p>§Reversible H1 receptor antagonists</p> <p>§Also considered “Inverse Agonists”</p> <p>§Block the binding of Histamine to its receptors</p> <p>§Three generations of Antihistamines</p> <p>§Each generation improved on the previous one</p> <p>§Share general characteristics and properties</p> <p>§</p> <p>§Small, lipophilic molecules that could cross the BBB</p> <p>§Not specific to the H1 receptor</p> <p>§Groups:</p> <p>§Ethylenediamines</p> <p>§Ethanolamines</p> <p>§Alkylamines</p> <p>§Piperazines</p> <p>§Tricyclics</p> <p>§Common structural features of classical antihistamine</p> <p>§2 Aromatic rings</p> <p>§Connected to a central Carbon, Nitrogen or CO</p> <p>§Spacer between the central X and the amine</p> <p>§Usually 2-3 carbons in length</p> <p>§Linear, ring, branched, saturated or unsaturated</p> <p>§Amine is substituted with small alkyl groups eg CH3</p> . You can play the slide in our in-built slide player or download for offline reading.
