• Gastroenterology
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Ileus: Causes, Symptoms and Treatment

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  • Updated on: 2025-05-23 21:43:37

Ileus is a temporary and functional (non-mechanical) arrest of intestinal peristalsis , leading to impaired movement of bowel contents through the small and/or large intestine .

Distinguishing Point : Unlike mechanical obstruction, ileus has no physical blockage . The bowel appears patent but lacks the muscular contractions to move contents forward.

Types of Intestinal Obstruction

  1. Mechanical Obstruction
    • Caused by a physical barrier in the intestine.
    • Examples: Volvulus , incarcerated hernia , intussusception , tumors , impacted feces , foreign bodies .
  2. Non-Mechanical Obstruction (Ileus)
    • Due to paralysis of intestinal musculature , not an anatomical blockage.
    • Also called paralytic ileus or adynamic ileus .
    • Most commonly seen postoperatively or due to intra-abdominal inflammation .

Etiology of Ileus

Common Causes

  • Postoperative ileus : Most frequent, especially after abdominal or pelvic surgery.
  • Peritonitis : Inflammation from infection (e.g., perforated viscus).
  • Retroperitoneal pathology :
    • Hematomas (e.g., ruptured AAA),
    • Inflammation (e.g., pancreatitis, retrocecal appendicitis),
    • Fractures (e.g., lumbar vertebrae).

Metabolic & Pharmacologic Causes

  • Electrolyte Imbalances : Hypokalemia, hypomagnesemia.
  • Drugs :
    • Opioids (↓ GI motility via μ-receptors),
    • Anticholinergics ,
    • Calcium channel blockers (less common).

Other Contributing Conditions

  • Renal failure
  • Thoracic causes (e.g., pneumonia, myocardial infarction, lower rib fractures)

Postoperative GI Recovery Timelines

GI Segment Normal Function Return
Small Intestine 0–24 hours
Stomach 24–48 hours
Colon 48–72 hours (most affected)

 

Clinical Presentation

  • Abdominal distention
  • Nausea and vomiting
  • Mild, vague abdominal discomfort
  • Obstipation (no flatus or stool) or minimal watery stool
  • Absent or hypoactive bowel sounds
  • Non-tender abdomen (unless underlying inflammation)

Pain is typically non-colicky , which helps differentiate from mechanical obstruction.

Diagnosis

Clinical Evaluation

  • History of recent surgery , trauma, infection, or medication use.
  • Absence of bowel sounds on auscultation .

Imaging

  • Abdominal X-ray :
    • Dilated loops of bowel with air-fluid levels.
    • Gas more prominent in the colon than in the small bowel (in postoperative ileus).
  • CT Scan :
    • Useful to rule out mechanical obstruction , abscess , or complication .

Contrast Studies

  • Water-soluble contrast enema or oral contrast can help distinguish ileus from mechanical obstruction.
  • In ileus, contrast may diffuse slowly through the bowel without a clear point of obstruction.

Management

Supportive Treatment

  • NPO (nil per os): No oral intake.
  • Nasogastric decompression : For vomiting or severe distention.
  • IV fluids and electrolyte correction , especially potassium .
  • Avoid opioids and anticholinergics (worsen motility).
  • Minimal sedation to preserve gut activity.

Maintain serum K⁺ > 4.0 mmol/L for optimal gut motility.

Persistent or Complicated Ileus

  • If symptoms persist > 5–7 days , suspect mechanical obstruction → Surgical consultation .
  • Colonic pseudo-obstruction (Ogilvie’s syndrome) :
    • Consider colonoscopic decompression .
    • IV neostigmine (cholinesterase inhibitor) may be used; cardiac monitoring required due to risk of bradycardia.

High-Yield Notes

  • Most common cause of ileus : Postoperative state
  • Classic triad : Abdominal distention + Vomiting + Absent bowel sounds
  • Initial step in management : Supportive care (NPO, fluids, NG tube)
  • Key complication to rule out : Mechanical obstruction or peritonitis
  • Ogilvie’s Syndrome = acute colonic pseudo-obstruction, often in elderly or immobile patients

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Dan Ogera

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